Download Advances in Corneal Research: Selected Transactions of the by A. J. Bron, J. M. Tiffany (auth.), Jonathan H. Lass (eds.) PDF

By A. J. Bron, J. M. Tiffany (auth.), Jonathan H. Lass (eds.)

`Almost each element of corneal learn and clinics is mentioned in various papers. This e-book can be recognized to everybody attracted to corneal clinics or research.'
Acta Ophthalmologica Scandinavica (1999)

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Extra info for Advances in Corneal Research: Selected Transactions of the World Congress on the Cornea IV

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Louis (1996). II. , Towards cytokine insight in sight. Brit. J. Ophthalmol. 79:970 (1995). 12. E. Langman, The immune system. Evolutionary principles. Guide to Our Understanding of This Complex Biological Defense System. Academic Press, London (1989). 13. V. , Placebo controlled trial of fusidic acid gel and oxytetracycline for recurrent blepharitis and rosacea. Brit. J. Ophthalmol. 79:42 (1995). 14. 1. , Drug resistance and acanthamoeba keratitis: the quest for alternative anti-protozoal chemotherapy.

It appears that chronically retained meibum can become pro-inflammatory and pro-metaplastic. A model candidate for such a meibomian inducer or mediator might, for example, be Leukotriene B4 (LTB4), a cytokine derived from arachidonic acid (a lipid substance released from phospholipid cell membranes). II LTB4 has been shown to cause epidermal hyperproliferation as well being a mediator of inflammation in vitro and in vivo. I I As an inducer of hyperproliferation, it could also contribute to primary obstruction of the meibomian duct by excessive epithelial growth, followed by hyperkeratinisation, with implications for the pathogenesis of (primary) obstructive meibomian dysfunction (OMD).

Clin. 34:27 (1994). 16. P. Gilbard, Non-toxic ophthalmic preparations. US Patent 4,775,531. Oct. 4, 1988. 5 BARRIER FUNCTION OF OCULAR SURFACE EPITHELIUM Shigeru Kinoshita, Norihiko Yokoi, and Aoi Komuro Department of Ophthalmology Kyoto Prefectural University of Medicine Kyoto, Japan ABSTRACT This paper demonstrates three different types of corneal epithelial barrier dysfunction: mechanically and/or immunologically oriented (as in superficial punctate keratopathy); genetically regulated (as in corneal dystrophy); and biologically based (as in conjunctival epithelial invasion of the cornea).

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